Review: Bladder Outlet Obstruction (BOO)

Diagnostic Tools
Clinical history, including the International Prostate Symtom Score (see APPENDIX A) or the AUA Symptom Score (see APPENDIX B)
Physical exam, including a digital rectal exam
Lab testing, including PSA and urinalysis
Additional tools include flow rates, PVR, cystoscopy, and urodynamics
   
BPH (Benign Prostatic Hyperplasia)
Progressive, age-related condition of men; linked to testicular androgens and aging
BPH leading to BOO is one potential etiology of LUTS (lower urinary tract symptoms)
Prostate size correlates poorly with the degree of symptoms exhibited by the individual patient
Intrusion of the prostate into the urethra and bladder neck leads to an obstructive process whereby higher pressure must be exerted by the detrusor (bladder muscle) to void. This leads to detrusor hypertrophy and urinary problems, including frequency, urgency, nocturia, and slowing of the urinary stream. These symptoms are not exclusive to BOO, and can also indicate diseases intrinsic to the bladder, neurogenic bladder, or failure to relax while voiding.
   
Symptom Scores
Help to sort out symptoms and validate diagnosis of BOO
Patients with high symptom scores should complete a bother score to assess how quality of life is affected
Symptom Scores may not correlate well with "Bother" Scores
Patients with low bother scores may wish to defer treatment; however, PVR should be assessed before making this decision
   
Physical Exam
Refer significant asymmetry, induration, or nodularity of the prostate to a urologist
Note any rectal mass
Test PSA; refer to urologist if elevated
Perform urinalysis to detect hematuria, pyuria, bacteriuria
   
Assessment of PVR
The BladderScan™ instrument (Diagnostic Ultrasound Corporation) provides a fast, easy, noninvasive way to determine PVR.
The BladderScan helps identify patients with high symptom scores who have developed chronic urinary retention; if these patients have low "bother" scores, they may require intervention based on high PVR, even if they aren't overly concerned about their symptoms.
The BladderScan also helps evaluate and manage patients with neurogenic bladder.
   
Treatment for BOO
Medical therapy - Includes alpha-blockers and finasteride (Proscar®, Avodart®)
Minimally Invasive Therapy - Thermal therapy (laser, microwave, high frequency radio wave); appropriate for the patient who cannot tolerate or fails to improve on medication, or prefers to have definitive therapy on initial treatment. Can be performed on an ambulatory or outpatient basis.
Surgical Therapy - TURP (transurethral resection of the prostate) is the gold standard for treatment of BOO; it provides the most lasting improvement in symptoms. Other surgical treatments include TUIP (transurethral incision of the prostate) and TUVP (transurethral vaporization of the prostate).
   
Conclusion: Monitoring Changes in Bladder Volume
Primary care physicians should have the ability to evaluate LUTS and recommend and monitor therapy for many common urinary conditions.
Symptom Scores and noninvasive bladder volume monitoring with the BladderScan are tools that will help primary care practices achieve the highest quality care for urological disease.
   
 

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