Abstract:
The Aging Bladder
M.B. Siroky, MD – Department of Urology, Boston
University School of Medicine, Boston, MA
Although
it is well established that lower urinary tract symptoms
increase in frequency with aging, there are few studies
of the mechanisms that underlie bladder dysfunction.
Age-related reduction in bladder capacity, uninhibited
contractions, decreased urinary flow rate, diminished
urethral pressure profile, and increased postvoid residual
volume warrant investigation and require differentiation
between symptoms associated with aging and those related
to comorbid conditions. Here, the current data are reviewed,
including those from muscle bath investigations of bladder
tissue contractility, in vivo studies using animal models,
and clinical studies in the aging population.
[Rev Urol. 2004; 6 (suppl 1): S3-S7]
If
you would like to read this study, please contact
us and we will send a copy to you. |